Trial no.:
|
PACTR202007628100458 |
Date of Approval:
|
13/07/2020 |
Trial Status:
|
Retrospective registration - This trial was registered after enrolment of the first participant |
|
TRIAL DESCRIPTION |
Public title
|
Photodynamic versus diode laser on the treatment of localized aggressive periodontitis |
Official scientific title |
Effect of photodynamic therapy versus diode laser therapy on the treatment of localized aggressive periodontitis. |
Brief summary describing the background
and objectives of the trial
|
Localized aggressive periodontitis(LAP) is a severe form of periodontal disease, that affects younger people, so it is a challenging disease, that needs rapid intervention. There are numerous treatment strategies including scaling and root planing (SRP), antibiotics, local drug delivery and surgical techniques for treatment of LAP. Nevertheless, they are associated with certain limitations. To overcome the limitations, antimicrobial photodynamic therapy (PDT) has been proposed as a treatment strategy for periodontal disease. The benefits of PDT include instant suppression of causative periopathogenic bacteria, minimum antibiotic resistance, absence of systemic disturbance and undesirable effects on the healthy periodontal tissue.
The aim of the present study is to evaluate the effect of diode laser alone versus PDT using indocyanine green in repeated form as adjunct to scaling and root planing on management of localized aggressive periodontitis clinically, immunologically and microbiologically. |
Type of trial |
RCT |
Acronym (If the trial has an acronym then please provide) |
|
Disease(s) or condition(s) being studied |
Oral Health |
Sub-Disease(s) or condition(s) being studied |
|
Purpose of the trial |
Treatment: Drugs |
Anticipated trial start date |
16/11/2017 |
Actual trial start date |
16/11/2017 |
Anticipated date of last follow up |
16/03/2019 |
Actual Last follow-up date |
16/03/2019 |
Anticipated target sample size (number of participants) |
45 |
Actual target sample size (number of participants) |
45 |
Recruitment status |
Completed |
Publication URL |
|
|