Trial no.:
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PACTR201512001348246 |
Date of Approval:
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15/11/2015 |
Trial Status:
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Registered in accordance with WHO and ICMJE standards |
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TRIAL DESCRIPTION |
Public title
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immediate implant using nanobone versus autogenous bone for treatment of patients with unrestorable single tooth. |
Official scientific title |
evaluation of surgical time, post-operative pain and marginal bone loss in immediate implant using "nanobone" versus "autogenous bone" for treatment of patients with unrestorable single tooth. |
Brief summary describing the background
and objectives of the trial
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A successful implant therapy require appropriate hard and soft tissue, perfect implant position, appropriate alveolar ridge architecture and integration of the implant. after tooth extraction bone resorption takes place and affect the quantity and quality of the bone resulting in inadequate bone volume for implant placement and future prosthetic restoration and impair the esthetic, so insertion of implant immediately following tooth extraction reduce bone loss and enhance esthetics.the fresh socket of extracted tooth is wider than the implant diameter and the distance between the implant and the bone called Peri-implant gap which influence the stability, osseointegration of the implants and esthetics. using bone graft in this gap between bone and implant enhance osseointegration and post-operative healing. autogenous bone graft considered the gold standard graft material for filling defects as it is osteogenic,osseoconductive and osseoinductive, however this approach obtained from the primary donor site for harvesting bone in the oral cavity which requires longer surgical procedure and produce not enough bone volume. there are several post-operative complication may happen as donor site morbidity and swelling,discomfort and pain, so alternative treatment has been suggested using biomaterials to fill the gap and reduce adverse effect of autogenous grafts.Several studies evaluate the success rate of implants with "autogenous" bone graft versus other synthetic guided bone regeneration materials. Nano porous grafting material as a new synthetic material "nanobone" nanocrystalline hydroxyapatite embedded in a porous silica gel matrix has oseoconductive and biomimetic properties integrate with the host bone. the sub-micron modification in bone substitutes enhance osteogenic property. the objective of this study is to measure surgical time, pain, implant stability and marginal bone loss in immediate implant placement with using autogenous bone graft versus nanobone graft. |
Type of trial |
RCT |
Acronym (If the trial has an acronym then please provide) |
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Disease(s) or condition(s) being studied |
Musculoskeletal Diseases,Unrestorable single tooth, fracture tooth in esthetic zone |
Sub-Disease(s) or condition(s) being studied |
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Purpose of the trial |
Treatment: Other |
Anticipated trial start date |
01/01/2016 |
Actual trial start date |
01/01/2016 |
Anticipated date of last follow up |
01/01/2018 |
Actual Last follow-up date |
01/01/2018 |
Anticipated target sample size (number of participants) |
18 |
Actual target sample size (number of participants) |
18 |
Recruitment status |
Recruiting |
Publication URL |
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