Trial no.:
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PACTR202106635355751 |
Date of Approval:
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02/06/2021 |
Trial Status:
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Retrospective registration - This trial was registered after enrolment of the first participant |
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TRIAL DESCRIPTION |
Public title
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Nutrition Support in Children with Severe Pneumonia |
Official scientific title |
Children’s Oxygen Administration Strategies Trial and Nutrition |
Brief summary describing the background
and objectives of the trial
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Worldwide, pneumonia is a major cause of death in children both during initial hospital admission and in the 6 months following discharge. The major risk factor for longterm mortality this is poor nutritional status. Currently no nutritional support is recommended for children without severe malnutrition. The COAST examines treatment recommendations regarding which children should receive oxygen. At 48 hours we then enrolled children into a nutrition trial: COAST Nutrition. This trial is examining whether supplementing the usual diet with a Ready-to-Use Therapeutic feed (usually given to children with severe malnutrition) for the following 56 days improves their outcomes (measured by better growth in terms of the fatness of their arms, called mid-upper arm circumference, and whether this improves survival 6months after their initial hospital admission. |
Type of trial |
RCT |
Acronym (If the trial has an acronym then please provide) |
COAST Nutrition |
Disease(s) or condition(s) being studied |
Paediatrics,Respiratory |
Sub-Disease(s) or condition(s) being studied |
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Purpose of the trial |
Treatment: Other |
Anticipated trial start date |
01/06/2018 |
Actual trial start date |
10/08/2018 |
Anticipated date of last follow up |
31/03/2022 |
Actual Last follow-up date |
17/10/2022 |
Anticipated target sample size (number of participants) |
840 |
Actual target sample size (number of participants) |
848 |
Recruitment status |
Completed |
Publication URL |
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