Trial no.:
|
PACTR202301487176282 |
Date of Approval:
|
16/01/2023 |
Trial Status:
|
Retrospective registration - This trial was registered after enrolment of the first participant |
|
TRIAL DESCRIPTION |
Public title
|
Comparative Study between Bupivacaine versus Bupivacaine with Dexmedetomidine in Ultrasound Guided Transversus Abdominis Plane Block as Postoperative Analgesia In Open Inguinal Hernia |
Official scientific title |
Comparative Study between Bupivacaine versus Bupivacaine with Dexmedetomidine in Ultrasound Guided Transversus Abdominis Plane Block as Postoperative Analgesia In Open Inguinal Hernia |
Brief summary describing the background
and objectives of the trial
|
postoperative pain leads to chronic pain and undesirable events ranging from patient discomfort and prolonged immobility to pulmonary complication . Expected pain prevalence following hernia repair was determined as 54%. Transversus abdominal plane block is one of the peripheral nerve blocks which was reported to reduce postoperative pain following hysterectomy, colorectal surgery, appendectomy, and inguinal hernia repair . transversus abdominis plane is located between the oblique muscles and the transversus abdominis muscles.
Transversus abdominis plane block basically involves deposition of local anesthetic in the plane between the internal oblique and transversus abdominis muscles to target the nerves passing through, that originate from thoracic level T6-T10 .
Dexmedetomidine is a selective alpha-2 adrenergic agonist with both analgesic and sedative properties, When administered as perineural adjuvant; it reduces initial blocking time also prolonging sensory and motor blockade duration. the objective of this study is to compare between Bupivacaine versus Bupivacaine with Dexmedetomidine in Ultrasound Guided Transversus Abdominis Plane Block as regardes efficacy, complications, quality and duration of postoperative analgesia.
|
Type of trial |
RCT |
Acronym (If the trial has an acronym then please provide) |
|
Disease(s) or condition(s) being studied |
Anaesthesia |
Sub-Disease(s) or condition(s) being studied |
|
Purpose of the trial |
Treatment: Drugs |
Anticipated trial start date |
25/08/2021 |
Actual trial start date |
27/08/2021 |
Anticipated date of last follow up |
27/08/2022 |
Actual Last follow-up date |
30/08/2022 |
Anticipated target sample size (number of participants) |
52 |
Actual target sample size (number of participants) |
52 |
Recruitment status |
Recruiting |
Publication URL |
Issuing authority/Trial register |
|