Trial no.:
|
PACTR201707002369196 |
Date of Approval:
|
20/06/2017 |
Trial Status:
|
Retrospective registration - This trial was registered after enrolment of the first participant |
|
TRIAL DESCRIPTION |
Public title
|
Studies of Continuous and Interval Exercise Training on Metabolic and Cardiovascular Health Indicators in Obese and Overweight Females |
Official scientific title |
Studies of Continuous and Interval Exercise Training on Metabolic and Cardiovascular Health Indicators in Obese and Overweight Females |
Brief summary describing the background
and objectives of the trial
|
Obesity is associated with some non ¿ communicable diseases. The major diseases associated with obesity include hypertension, diabetes mellitus, and atherosclerosis, as well as certain types of cancer; there are also many additional less known complications of the disease (Bray, 1985). Overweight and obesity now ranks as the fifth highest global risk factor for mortality and is the cause of an estimated 35.8 million (2.3%) of global DALYs (disability-adjusted life years) lost (WHO, 2010). In a systematic review on the prevalence of overweight and obesity of adult Nigerians, Chukwuonye et al. (2013) reported that the prevalence of overweight and obese individuals in Nigeria is of epidemic proportions. There is therefore, a need to pay closer attention to combating these health disorders. People generally become obese when, over a period of time, their energy intake exceeds their energy expenditure (National Institute for Health & Clinical Excellence (NICE), 2006). There is epidemiological evidence that an inverse relationship exists between physical activity and body weight, and that body fat is more favourably distributed in individuals who are physically active (Anderson et al., 1991; Wing et al., 1991 and Di Pietro, 1995).
Studies have shown that both continuous endurance exercise as well as high-intensity interval exercise increase fat oxidation post-training, but it is unclear which training protocol elicits the greater adaptation in overweight and obese females (Manning, 2011).Therefore, this study is designed to assess the efficacy of two different training modes of exercise in reversing the anthropometric, cardiovascular and metabolic features of overweight and obesity in females. This study will contribute to the recent recommendations to explore further the effective mechanism of exercise training in weight management. The result from this study will also contribute to the already existing guidelines for exercise prescription in weight management. |
Type of trial |
RCT |
Acronym (If the trial has an acronym then please provide) |
|
Disease(s) or condition(s) being studied |
Genetic Diseases,Nutritional, Metabolic, Endocrine,Obesity |
Sub-Disease(s) or condition(s) being studied |
|
Purpose of the trial |
Physical activity and nutrition |
Anticipated trial start date |
11/01/2016 |
Actual trial start date |
07/03/2016 |
Anticipated date of last follow up |
14/07/2017 |
Actual Last follow-up date |
|
Anticipated target sample size (number of participants) |
105 |
Actual target sample size (number of participants) |
97 |
Recruitment status |
Closed to recruitment,follow-up continuing |
Publication URL |
|
|