Trial no.:
|
PACTR201804002955302 |
Date of Approval:
|
09/01/2018 |
Trial Status:
|
Retrospective registration - This trial was registered after enrolment of the first participant |
|
TRIAL DESCRIPTION |
Public title
|
USEFULNESS OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING CAESAREAN DELIVERY IN IBADAN |
Official scientific title |
EFFECT OF INTRAVENOUS TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING CAESAREAN DELIVERY: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL |
Brief summary describing the background
and objectives of the trial
|
Background: The rate of caesarean delivery has increase to about 25-30% in many areas of the world and one of its major complications is haemorrhage which remains the leading cause of admission in intensive care unit and the most preventable cause of maternal mortality. American College of Obstetricians and Gynaecologists (ACOG) evaluation of caesarean deliveries found that overall mortality rate from caesarean delivery is 6/100,000 which is 3-7 times greater than that of vaginal delivery. Recent studies have also shown that primary caesarean delivery increases the risk of blood transfusion to about 4.2 times higher than vaginal delivery.
Objective: To evaluate the efficacy of tranexamic acid in reducing blood loss in patients undergoing caesarean delivery. |
Type of trial |
CCT |
Acronym (If the trial has an acronym then please provide) |
|
Disease(s) or condition(s) being studied |
Circulatory System,HAEMORRHAGE,Pregnancy and Childbirth |
Sub-Disease(s) or condition(s) being studied |
|
Purpose of the trial |
Prevention |
Anticipated trial start date |
11/11/2015 |
Actual trial start date |
28/01/2016 |
Anticipated date of last follow up |
10/11/2016 |
Actual Last follow-up date |
20/05/2016 |
Anticipated target sample size (number of participants) |
71 |
Actual target sample size (number of participants) |
154 |
Recruitment status |
Completed |
Publication URL |
|
|