Pan African Clinical Trials Registry
South African Medical Research Council, South African Cochrane Centre
PO Box 19070, Tygerberg, 7505, South Africa
Telephone: +27 21 938 0506 / +27 21 938 0834 Fax: +27 21 938 0836
Email: pactradmin@mrc.ac.za Website: pactr.samrc.ac.za
Trial no.: PACTR202604865314027 Date of Registration: 21/04/2026
Trial Status: Retrospective registration - This trial was registered after enrolment of the first participant
TRIAL DESCRIPTION
Public title Education Program to reduce occupational burnout among nurses
Official scientific title Effectiveness of an environmental Education Program on knowledge and practice of nursing personnel regarding occupational burnout at medical research Institute hospital -Alexandria University
Brief summary describing the background and objectives of the trial Burnout syndrome has been defined as the experience of long-term exhaustion and diminished interest, usually in the work context. Nursing is a stressful profession that deals with intense human aspects of health and illness. The stressful nature of nursing profession can ultimately lead to job dissatisfaction and burnout. Moreover, the closeness to the patients and the strong emotional involvement that result from this, often makes nursing a particularly demanding profession and produce additional forms of nurses' burnout. Occupational burnout has significant implications on the individual, healthcare organizations, and the patient population. The first implication is the individual ‘s unfavorable quality of life, including multiple physical and mental health problems. The second implication of occupational burnout is the negative impact on the organizations. It has been found that burnout may lead to reduced nurses work appointment, increase absenteeism, lower levels of job satisfaction, inefficiency in innovative capabilities and loss of productivity. This study aims to evaluate and enhance the management of job burnout among nursing personnel. Initially, the research assesses current knowledge and scores of burnout to establish a baseline. Based on these findings, an educational program will be designed and implemented to address identified gaps. Finally, the study will measure the program's effectiveness by comparing participants' knowledge and burnout score before and after the intervention to determine its overall impact.
Type of trial Non-Randomised
Acronym (If the trial has an acronym then please provide)
Disease(s) or condition(s) being studied Mental and Behavioural Disorders
Sub-Disease(s) or condition(s) being studied
Purpose of the trial Education /Training
Anticipated trial start date 04/08/2025
Actual trial start date 02/09/2025
Anticipated date of last follow up 17/02/2026
Actual Last follow-up date
Anticipated target sample size (number of participants) 100
Actual target sample size (number of participants) 100
Recruitment status Completed
Publication URL
Secondary Ids Issuing authority/Trial register
STUDY DESIGN
Intervention assignment Allocation to intervention If randomised, describe how the allocation sequence was generated Describe how the allocation sequence/code was concealed from the person allocating the participants to the intervention arms Masking If masking / blinding was used
Single Group Non-randomised Allocation was determined by the holder of the sequence who is situated off site Open-label(Masking Not Used)
INTERVENTIONS
Intervention type Intervention name Dose Duration Intervention description Group size Nature of control
Experimental Group Educational sessions three educational sessions per group. Each session lasts for 45-60 minutes. one week apart between subsequent sessions. The 100 participants will be divided into 4 equal groups each has 25 participants. three weeks educational program The educational intervention consists of three structured sessions, designed to provide a comprehensive understanding of occupational burnout. Session 1 establishes a foundational knowledge base, covering definitions, risk factors, components, and the specific problems within healthcare settings that contribute to burnout. Session 2 shifts the focus to the broader consequences, analyzing the hazards of burnout and its adverse impacts on human health, patient care, and organizational stability. Finally, Session 3 emphasizes solutions by introducing management systems, the strategic benefits of environmental and safety programs, and the scope of governmental responsibilities. To ensure maximum engagement and knowledge retention, the program utilizes diverse instructional methods, including interactive lectures and collaborative discussions. 100
ELIGIBILITY CRITERIA
List inclusion criteria List exclusion criteria Age Category Minimum age Maximum age Gender
Nursing Personnel currently working at Medical Research Institute hospital in Alexandria University and have been work for at least one Year in the hospital. those in vacation and those who worked for less than 1 year in the institute. Adult: 18 Year(s)-44 Year(s),Middle Aged: 45 Year(s)-64 Year(s) 18 Year(s) 50 Year(s) Both
ETHICS APPROVAL
Has the study received appropriate ethics committee approval Date the study will be submitted for approval Date of approval Name of the ethics committee
Yes 29/04/2025 the Institutional Ethics Committee of the High Institute of Public Health at Alexandria University
Ethics Committee Address
Street address City Postal code Country
165 el horeya street Alexandria 21561 Egypt
OUTCOMES
Type of outcome Outcome Timepoint(s) at which outcome measured
Primary Outcome burnout score before and after the intervention program before the intervention and then immediately after and after 3 month of the intervention.
Secondary Outcome assess knowledge about occupational burnout before the intervention and then immediately after and after 3 month of the intervention.
RECRUITMENT CENTRES
Name of recruitment centre Street address City Postal code Country
Medical Research Institute hospital at Alexandria University 165 el horeya street Alexandria 21562 Egypt
FUNDING SOURCES
Name of source Street address City Postal code Country
Mohamed Fakhry Hussein El Asafra Street Alexandria 22412 Egypt
SPONSORS
Sponsor level Name Street address City Postal code Country Nature of sponsor
Primary Sponsor the High Institute of Public Health at Alexandria University 165 el horeya street Alexandria 21561 Egypt University
COLLABORATORS
Name Street address City Postal code Country
CONTACT PEOPLE
Role Name Email Phone Street address
Principal Investigator Mohamed Hussein hiph-mohamedfakhry@alexu.edu.eg +201271266332 El Asafra Street
City Postal code Country Position/Affiliation
Alexandria 22412 Egypt Associate Professor of Public Health at High Institute of Public Health
Role Name Email Phone Street address
Scientific Enquiries Mohamed Hussein hiph-mohamedfakhry@alexu.edu.eg +201271266332 El Asafra Street
City Postal code Country Position/Affiliation
Alexandria 22412 Egypt Associate Professor of Public Health at High Institute of Public Health
Role Name Email Phone Street address
Public Enquiries Manal Abdelrazek hiph.manalmohammed@alexu.edu.eg +201288704751 El hadara street
City Postal code Country Position/Affiliation
Alexandria 25146 Egypt Head Nurse at Medical Research Institute Hospital at Alexandria University
REPORTING
Share IPD Description Additional Document Types Sharing Time Frame Key Access Criteria
Yes IPD will be shared. Individual participant data will be available after de-identifying individual trial participant data (text, tables, figures, and appendices). A statistical analysis plan and analytic code will also be available. It will be immediately after publication for the researchers who wish to access the data to achieve the aims of the approved proposal. proposal should be directed to hiph-mohamedfakhry@alexu.edu.eg Study Protocol data will be available just after publication, with no end date all researchers who are interested in the study.
URL Results Available Results Summary Result Posting Date First Journal Publication Date
https://drive.google.com/file/d/15zrbwdhSPqE--UBDEwVXqsBw81TvMdpw/view?usp=sharing No
Result Upload 1: Result Upload 2: Result Upload 3: Result Upload 4: Result Upload 5:
Result URL Hyperlinks Link To Protocol
Result URL Hyperlinks
Changes to trial information
Section Name Field Name Date Reason Old Value Updated Value
Eligibility Age group 31/03/2026 we ticked all applicable age groups Adult: 19 Year-44 Year Adolescent: 13 Year-18 Year, Adult: 19 Year-44 Year, Middle Aged: 45 Year(s)-64 Year(s)
Section Name Field Name Date Reason Old Value Updated Value
Eligibility Age group 21/04/2026 PACTR Admin Adolescent: 13 Year(s)-17 Year(s), Adult: 18 Year(s)-44 Year(s), Middle Aged: 45 Year(s)-64 Year(s) Adult: 18 Year(s)-44 Year(s), Middle Aged: 45 Year(s)-64 Year(s)
Section Name Field Name Date Reason Old Value Updated Value
Intervention Intervention List 31/03/2026 we changed the name of intervention name to be Educational intervention to express the intervention that is implemented Experimental Group, burnout intervention group, three educational sessions per group. Each session lasts for 45-60 minutes. one week apart between subsequent sessions. The 100 participants will be divided into 4 equal groups each has 25 participants., three weeks educational program, The educational intervention consists of three structured sessions, designed to provide a comprehensive understanding of occupational burnout. Session 1 establishes a foundational knowledge base, covering definitions, risk factors, components, and the specific problems within healthcare settings that contribute to burnout. Session 2 shifts the focus to the broader consequences, analyzing the hazards of burnout and its adverse impacts on human health, patient care, and organizational stability. Finally, Session 3 emphasizes solutions by introducing management systems, the strategic benefits of environmental and safety programs, and the scope of governmental responsibilities. To ensure maximum engagement and knowledge retention, the program utilizes diverse instructional methods, including interactive lectures and collaborative discussions., 100, Experimental Group, Educational intervention , three educational sessions per group. Each session lasts for 45-60 minutes. one week apart between subsequent sessions. The 100 participants will be divided into 4 equal groups each has 25 participants., three weeks educational program, The educational intervention consists of three structured sessions, designed to provide a comprehensive understanding of occupational burnout. Session 1 establishes a foundational knowledge base, covering definitions, risk factors, components, and the specific problems within healthcare settings that contribute to burnout. Session 2 shifts the focus to the broader consequences, analyzing the hazards of burnout and its adverse impacts on human health, patient care, and organizational stability. Finally, Session 3 emphasizes solutions by introducing management systems, the strategic benefits of environmental and safety programs, and the scope of governmental responsibilities. To ensure maximum engagement and knowledge retention, the program utilizes diverse instructional methods, including interactive lectures and collaborative discussions., 100,
Section Name Field Name Date Reason Old Value Updated Value
Intervention Intervention List 21/04/2026 PACTR Admin Experimental Group, Educational intervention , three educational sessions per group. Each session lasts for 45-60 minutes. one week apart between subsequent sessions. The 100 participants will be divided into 4 equal groups each has 25 participants., three weeks educational program, The educational intervention consists of three structured sessions, designed to provide a comprehensive understanding of occupational burnout. Session 1 establishes a foundational knowledge base, covering definitions, risk factors, components, and the specific problems within healthcare settings that contribute to burnout. Session 2 shifts the focus to the broader consequences, analyzing the hazards of burnout and its adverse impacts on human health, patient care, and organizational stability. Finally, Session 3 emphasizes solutions by introducing management systems, the strategic benefits of environmental and safety programs, and the scope of governmental responsibilities. To ensure maximum engagement and knowledge retention, the program utilizes diverse instructional methods, including interactive lectures and collaborative discussions., 100, Experimental Group, Educational sessions, three educational sessions per group. Each session lasts for 45-60 minutes. one week apart between subsequent sessions. The 100 participants will be divided into 4 equal groups each has 25 participants., three weeks educational program, The educational intervention consists of three structured sessions, designed to provide a comprehensive understanding of occupational burnout. Session 1 establishes a foundational knowledge base, covering definitions, risk factors, components, and the specific problems within healthcare settings that contribute to burnout. Session 2 shifts the focus to the broader consequences, analyzing the hazards of burnout and its adverse impacts on human health, patient care, and organizational stability. Finally, Session 3 emphasizes solutions by introducing management systems, the strategic benefits of environmental and safety programs, and the scope of governmental responsibilities. To ensure maximum engagement and knowledge retention, the program utilizes diverse instructional methods, including interactive lectures and collaborative discussions., 100,